Progeria is a rare and fatal genetic disease of accelerated aging in children. Without the discovery of new treatments, all children with Progeria will die of heart disease at an average age of 14 years. The Progeria Research Foundation (PRF) was founded in 1999 in response to the complete lack of progress being made to help children with Progeria. Our original mission: to discover the cause, treatments and cure for Progeria.* Today, PRF continues to be the only organization in the world solely dedicated to this mission. We have filled a void, taking these children out of the background where they had been for over 100 years and putting them and Progeria at the forefront of scientific efforts.
In just 13 years, we have achieved extraordinary progress towards our mission: the Progeria gene discovery in 2003, first-ever clinical drug trials initiated in 2007, and the 2012 results of that first trial being the discovery of the first treatment for Progeria. In addition, we have achieved extensive global awareness of the disease and PRF's work, and confirmation of critical biological links between Progeria, heart disease and aging we all experience. From an obscure, ignored disease to treatment and global recognition – an unheard of timeline in the world of medical research! Our accomplishments are being praised as a “scientific sprint”** as we forge ahead in this race against time.
All of this progress is due in large part to the creation of PRF's research-related programs and services. Developed with insightful determination, they provide the resources needed not only to advance the field of Progeria, but also to discover what Progeria can tell us about heart disease and aging.
With the support of dedicated staff and volunteers, a talented board of directors, courageous families, and thousands of generous people around the world, we are pushing the field of Progeria forward towards discovery, treatments, and cure. And along the way, we are learning a tremendous amount about ourselves.
Learn more about Progeria and what you can do to help at the Progeria Research Foundation Website: progeriaresearch.org.
PRF has achieved a tremendous amount in its 13-year history, but there’s much more work to be done to achieve our ultimate goal of a cure. You can help - donate now and help us find a cure.